New York Giants vs Washington Commanders picks, odds for NFL Week 1

The New York Giants and Washington Commanders play on Sunday, Sept. 7 at the Commanders’ Northwest Stadium in a game on the NFL Week 1 schedule.

Which team will win the NFL Week 1 game?

Check out these NFL Week 1 picks and NFL Week 1 predictions for the game, which can be seen at 10 a.m. MST on FOX (stream with FUBO).

The Commanders are a 6-point favorite over the Giants in NFL Week 1 odds for the game, courtesy of BetMGM Sportsbook.

Washington is -275 on the moneyline, while New York is +220. The over/under (point total) is set at 45.5 points.

NFL Week 1 picks: Cowboys vs Eagles | Chiefs vs Chargers | Buccaneers vs Falcons | Bengals vs Browns | Dolphins vs Colts | Panthers vs Jaguars | Raiders vs Patriots | Cardinals vs Saints | Steelers vs Jets | Giants vs Commanders | Titans vs Broncos | 49ers vs Seahawks | Lions vs Packers | Texans vs Rams | Ravens vs Bills | Vikings vs Bears | The Republic’s score predictions

Watch Giants at Commanders live on FUBO (free trial)

Jeremy Cluff writes: “The NFL QB carousel put Russell Wilson with the Giants. How long will he be the starting QB? Some whispers might be heard if he has a slow start against the Commanders.”

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BetMGM: Bet the Giants with the points vs Commanders

Nick Hennion writes: “Based on the Commanders’ penchant for playing close games and Russell Wilson’s ATS success as a dog, my Commanders vs Giants prediction is the Giants Spread (+7, -115). My initial reaction to this line is that it’s likely to prove a popular parlay and teaser leg in favor of the Commanders. Last season, Washington finished 2-0 against the Giants. But New York stayed within this number on both occasions. In Week 2 at Washington, New York lost by three in a game where their kicker aggravated an injury on the first play of the game.”

NFL Week 1 odds: Point spreads, moneylines, over/unders for betting on games

The site’s formula predicts that the Commanders will win the NFL Week 1 game against the Giants.

NFL Week 1 schedule: Television channels, how to watch, stream games

ESPN: Commanders have a 69% chance to beat Giants on Sunday

The site gives the Giants a 30.7% shot at winning the NFL Week 1 game, with the remaining percentage accounting for a tie.

NFL power rankings Week 1: Where are Commanders, Giants?

Dimers: Commanders 26, Giants 20

It writes: “After extensive simulations, our model gives the Giants a win probability of 28%, while the Commanders have a win probability of 72%.”

Fansided: Giants 17, Commanders 16

Lou Scataglia writes: “Could the New York Giants score an upset in Week 1? If nothing else, their defensive line is going to feast all year and get to the QB at a high level, and with Washington not having the best offensive line, there is a path for the G-Men to win if it’s a low-scoring affair.”

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Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.

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