Houston will counter with Hunter Brown, who is having the best season of his career with a 2.51 ERA in 23 starts. Brown earned his first All-Star selection last month.
First pitch in Houston is at 7:10 p.m. Eastern. Here’s a preview.
RED SOX (66-55): Anthony LF, Bregman 3B, Duran CF, Story SS, Yoshida DH, Gonzalez 1B, Abreu RF, Rafaela 2B, Wong C
Pitching: RHP Walker Buehler (7-6, 5.40 ERA)
ASTROS (67-53): Pena SS, Sanchez LF, Altuve 2B, Walker 1B, Caratini DH, Diaz C, Urias 3B, Smith RF, Melton CF
Pitching: RHP Hunter Brown (9-5, 2.51 ERA)
Time: 7:10 p.m.
TV, radio: NESN, WEEI-FM 93.7
Red Sox vs. Brown: Wilyer Abreu 0-4, Roman Anthony 1-3, Alex Bregman 2-3, Jarren Duran 1-5, Carlos Narváez 0-2, Ceddanne Rafaela 2-5, Trevor Story 0-2, Abraham Toro 1-6, Connor Wong 1-2, Masataka Yoshida 0-4
Astros vs. Buehler: Jose Altuve 1-8, Victor Caratini 3-10, Carlos Correa 3-7, Yainer Diaz 2-3, Mauricio Dubón 1-5, Cam Smith 0-2, Jesús Sánchez 2-7, Taylor Trammell 1-1, Ramón Urías 2-4, Christian Walker 6-27
Stat of the day: The Red Sox scored 10-plus runs for the 19th time this season on Tuesday.
Notes: In his second outing with the Red Sox, May struck out eight and walked one. He tossed six scoreless innings for just the fourth time in his career. “I definitely try to ride the highs,” May said. “I had a lot of lows this year, so whenever I do have the good moments, I try to let my brain know that ‘hey, you got it, it’s still in you for sure.’ ” … Roman Anthony has homered twice in his last two games after homering twice in his first 50. He became the fourth Red Sox player to homer in back-to-back games at age 21 or younger, joining Ted Williams, Tony Conigliaro, and Rafael Devers. Anthony also drew four walks Tuesday. “I understand the quality of hitters I have behind me, so it makes my life easier,” Anthony said. “I’m more than glad to take my walks.” … Buehler is 1-1 with a 3.72 ERA in four career starts against the Astros. He tossed 4 ⅓ innings against Houston on Aug. 2, allowing three earned runs and settling for a no decision in a Sox win at Fenway. … Brown made his only career start against Boston on Aug. 1, allowing just one earned run on four hits over seven innings, but also had to settle for a no decision in another Sox win.
Amin Touri can be reached at amin.touri@globe.com.