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Hispanic Business TV > Sports > NFL > NFL Week 6 predictions, win probabilities, picks for games this week
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NFL Week 6 predictions, win probabilities, picks for games this week

HBTV
Last updated: October 8, 2025 7:42 pm
HBTV
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Contents
Thursday Night Football prediction, Oct. 9Sunday international game in London prediction, Oct. 12Sunday early NFL game predictions, Oct. 12Sunday late NFL game predictions, Oct. 12Sunday Night Football prediction, Oct. 12Monday Night Football prediction, Oct. 13
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NFL Week 5 Overreactions

USAT’s Lorenzo Reyes breaks down the best games from NFL Week 5.

Sports Seriously

Which NFL teams have the best chances of winning their games on the NFL Week 6 schedule?

ESPN Analytics has revealed its Matchup Predictor numbers for the 15 games in the league this week, and they offer some interesting win probabilities.

Take a look at the site’s picks for this week’s NFL games, beginning with the Thursday Night Football game between the Philadelphia Eagles and New York Giants and ending with the Monday Night Football games between the Buffalo Bills and Atlanta Falcons and Chicago Bears and Washington Commanders.

Some of the site’s predictions differ from NFL Week 6 odds and other NFL Week 6 picks for NFL Week 6 games.

How correct will the analytics be this week? Click on each game for more NFL Week 6 predictions for that NFL matchup. All times MST. The site allows for the possibility of ties, so the numbers add up to just less than 100%.

NFL Week 6 picks: Eagles at Giants | Broncos vs Jets | Rams at Ravens | Cowboys at Panthers | Cardinals at Colts | Seahawks at Jaguars | Chargers at Dolphins | Browns at Steelers | Patriots at Saints | Titans at Raiders | 49ers at Buccaneers | Bengals at Packers | Lions at Chiefs | Bills at Falcons | Bears at Commanders | The Republic’s score predictions

Watch NFL games on FUBO (free trial)

Thursday Night Football prediction, Oct. 9

Philadelphia Eagles at New York Giants, 5:15 p.m., Prime Video (stream on Amazon)

Eagles have a 74.8% chance to beat Giants on Thursday Night Football.

The site gives the Giants a 25% shot at winning the NFL Week 6 game, with the remaining percentage accounting for a tie.

NFL Week 6 picks: Predictions for who will win every game this week

Sunday international game in London prediction, Oct. 12

Denver Broncos vs New York Jets, 6:30 a.m., NFL Network (stream with FUBO)

Broncos have a 71% chance to beat Jets on Sunday.

The site gives the Jets a 28.8% shot at winning the NFL Week 6 game, with the remaining percentage accounting for a tie.

NFL power rankings Week 6: Improbable comebacks, collapses shake up rankings

Sunday early NFL game predictions, Oct. 12

Los Angeles Rams at Baltimore Ravens, 10 a.m., FOX (stream with FUBO)

Rams have a 59.6% chance to beat Ravens on Sunday.

The site gives the Ravens a 40.1% shot at winning the NFL Week 6 game, with the remaining percentage accounting for a tie.

Dallas Cowboys at Carolina Panthers, 10 a.m., FOX (stream with FUBO)

Cowboys have a 60.8% chance to beat Panthers on Sunday.

The site gives the Panthers a 38.9% shot at winning the NFL Week 6 game, with the remaining percentage accounting for a tie.

Arizona Cardinals at Indianapolis Colts, 10 a.m., FOX (stream with FUBO)

Colts have a 65.1% chance to beat Cardinals on Sunday.

The site gives the Cardinals a 34.7% shot at winning the NFL Week 6 game, with the remaining percentage accounting for a tie.

Seattle Seahawks at Jacksonville Jaguars, 10 a.m., FOX (stream with FUBO)

Seahawks have a 50.3% chance to beat Jaguars on Sunday.

The site gives the Jaguars a 49.3% shot at winning the NFL Week 6 game, with the remaining percentage accounting for a tie.

Los Angeles Chargers at Miami Dolphins, 10 a.m., CBS (stream with FUBO)

Chargers have a 60.4% chance to beat Dolphins on Sunday.

The site gives the Dolphins a 39.3% shot at winning the NFL Week 6 game, with the remaining percentage accounting for a tie.

Cleveland Browns at Pittsburgh Steelers, 10 a.m., CBS (stream with FUBO)

Steelers have a 64.2% chance to beat Browns on Sunday.

The site gives the Browns a 35.5% shot at winning the NFL Week 6 game, with the remaining percentage accounting for a tie.

New England Patriots at New Orleans Saints, 10 a.m., CBS (stream with FUBO)

Patriots have a 60.4% chance to beat Saints on Sunday.

The site gives the Saints a 39.3% shot at winning the NFL Week 6 game, with the remaining percentage accounting for a tie.

NFL Week 6 odds: Point spreads, moneylines, over/unders for betting on games this week

Sunday late NFL game predictions, Oct. 12

Tennessee Titans at Las Vegas Raiders, 1:05 p.m., FOX (stream with FUBO)

Raiders have a 64.4% chance to beat Titans on Sunday.

The site gives the Titans a 35.3% shot at winning the NFL Week 6 game, with the remaining percentage accounting for a tie.

San Francisco 49ers at Tampa Bay Buccaneers, 1:25 p.m., CBS (stream with FUBO)

Buccaneers have a 51.1% chance to beat 49ers on Sunday.

The site gives the 49ers a 48.5% shot at winning the NFL Week 6 game, with the remaining percentage accounting for a tie.

Cincinnati Bengals at Green Bay Packers, 1:25 p.m., CBS (stream with FUBO)

Packers have an 80.1% chance to beat Bengals on Sunday.

The site gives the Bengals a 19.7% shot at winning the NFL Week 6 game, with the remaining percentage accounting for a tie.

NFL Week 6 schedule: TV channels, how to watch, how to stream games this week

Sunday Night Football prediction, Oct. 12

Detroit Lions at Kansas City Chiefs, 5:20 p.m., NBC (stream on Peacock)

Chiefs have a 53.4% chance to beat Lions on Sunday Night Football.

The site gives the Lions a 46.3% shot at winning the NFL Week 6 game, with the remaining percentage accounting for a tie.

NFL Week 6 announcers: Television broadcasters, announcing crews for NFL Week 6 schedule

Monday Night Football prediction, Oct. 13

Buffalo Bills at Atlanta Falcons, 4:15 p.m., ESPN (stream with FUBO)

Bills have a 60.7% chance to beat Falcons on Monday Night Football.

The site gives the Falcons a 39% shot at winning the NFL Week 6 game, with the remaining percentage accounting for a tie.

Chicago Bears at Washington Commanders, 5:15 p.m., ABC (stream with FUBO)

Commanders have a 64.5% chance to beat Bears on Monday Night Football.

The site gives the Bears a 35.2% shot at winning the NFL Week 6 game, with the remaining percentage accounting for a tie.

The Houston Texans and Minnesota Vikings are off this week.

NFL’s highest paid players in 2025: Quarterbacks | Running backs | Wide receivers | Tight ends | Offensive linemen | D-linemen | Cornerbacks | Safeties | Linebackers | Edge rushers | Highest paid NFL players: Overall | By position | By team

Reach Jeremy Cluff at jeremy.cluff@arizonarepublic.com. Follow him on X, formerly Twitter @Jeremy_Cluff.

Support local journalism: Subscribe to azcentral.com today. Sign up for azcentral Preps Now. And be sure to subscribe to our daily sports newsletters so you don’t miss a thing.





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